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January 15, 2021
Editorial Article: Harnessing 19F as an agent in bio-NMR of large systems Watch this on-demand webinar to learn more about emerging and cutting-edge techniques in NMR 14 Jan 2021 The 19F- 13C TROSY principle opens exciting opportunities to probe structure, dynamics and interactions in large biomolecular systems, in which 19F-labels can be incorporated into either a protein or a nucleic acid residue. The fluorine atom is an extremely sensitive probe towards its chemical environment thanks to...
January 11, 2021
Editorial Article: Max Planck pioneers push boundaries in stem cell biology with the humble flatworm Discover how researchers are harnessing novel slide-scanning technology to improve the understanding of regenerative biology 15 Jan 2021 Adult flatworm stem cells floating in suspension More commonly known as planarians to scientists, the flatworm possesses a remarkable ability that has for some time now caught the attention of stem cell biologists and others. These flatworms have an astonishing...
January 8, 2021
Q: Which technique is most effective for the detection of NDMA, LC-MS or GC-MS? JS: You can use both. The main thing to consider is to use a triple quadrupole instead of a single quad method; this gives a higher level of specificity as the molecular weight of the analytes is low. One other thing to consider with GC-MS is the high temperatures — this can result in the breakdown of your samples and produce false positives, but at the moment the authorities are releasing methods on both LC- and ...
January 8, 2021
Editorial Article: The quest for precision medicine: Decoding cancer pathogenesis and overcoming drug resistance Dr. Komal Kumar Javarappa shares insights from the multidisciplinary forefront of immuno-oncology, where translational biologists race against time to optimize new cancer therapies 08 Jan 2021 Dr. Komal Kumar Javarappa Blood cancers such as multiple myeloma and acute myeloid leukemia (AML) are relatively rare but often result in worse prognoses compared to many other cancer types. ...
January 7, 2021
Editorial Article: Improved LC-MS analysis of oligonucleotides with next-generation chromatography Watch this on-demand webinar to learn how metal interactions with oligonucleotides impact LC-MS performance, sensitivity and reproducibility 07 Jan 2021 Dr. Martin Gilar, Scientific Fellow at Waters Accelerated development of oligonucleotides for both therapeutic and diagnostic applications is driving a need for more precise and productive analytical testing of these molecules. One challenge is ...
January 7, 2021
Editorial Article: Take control over your chromatographic separations: It’s your loss Discover how to minimize the loss of metal-sensitive analytes and achieve fast analysis and high recovery of oligonucleotides 07 Jan 2021 ACQUITY PREMIER Columns from Waters Analyte loss due to non-specific adsorption is a well-known problem among separations scientists that has long plagued chromatography analyses. Often a result of unwanted interactions with the interior wall of steel analytical columns, t...
January 7, 2021
Editorial Article: Virtual Analytical Summit 2021: Registration now open Connecting the scientific community through a content-rich online event - reserve your place free today 07 Jan 2021 Scientists and scientific manufacturers from across the world are being invited to participate in the upcoming SelectScience Registration is now open for this free-to-attend Virtual Summit that will feature presentations by leading scientists and technology innovators, video interviews, virtual resource hubs,...
January 6, 2021
Gene modulation in primary human immune cells: Successful strategies and applications for CRISPRko, RNAi and beyond Expert Insight: Gene modulation in primary human immune cells: Successful strategies and applications for CRISPRko, RNAi and beyond Watch this on-demand webinar to learn more about manipulating the genes within physiologically relevant human immune cells 05 Jan 2021 Dr. Verena Brucklacher-Waldert, Horizon Discovery. In this on-demand SelectScience webinar, immunology expert Dr. Ve...
December 23, 2020
Editorial Article: Virtual Analytical Summit 2021: Registration now open Connecting the scientific community through a content-rich online event - reserve your place free today 07 Jan 2021 Scientists and scientific manufacturers from across the world are being invited to participate in the upcoming SelectScience Registration is now open for this free-to-attend Virtual Summit that will feature presentations by leading scientists and technology innovators, video interviews, virtual resource hubs,...
December 23, 2020
Editorial Article: Food safety: Tackling the global PFAS contamination crisis with mass spec Marco Zhong, Director of the National Reference Laboratory for Food Contact Material, discusses ‘forever chemicals’ and why effective FCM testing is more important than ever 23 Dec 2020 Marco Zhong, Director of the National Reference Laboratory for Food Contact Material, Guangdong Increased awareness around the potential threat to human health of perfluoroalkyl and polyfluoroalkyl substances (PFAS) ...