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Study shows how SARS-CoV-2 Omicron evades our immune response and remains infective

A recent study published in the journal Science brings a detailed chemical and molecular perspective on the improved evasion of antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the retention of strong interactions with the receptor as two principal factors underneath the notorious transmissibility of the SARS-CoV-2 Omicron variant.
United Kingdom British Columbia Abc Center Disease Control Public Health Laboratory World Health Organization Department Of Biochemistry

Exploring the structural basis of antibody evasion and enhanced transmission of the SARS-CoV-2 Omicron variant

In a new study, researchers used cryogenic electron microscopy (cryo-EM) analysis to capture the open and closed states of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variantโ€™s spike protein.
Image Credit Graphpad Prism Coronavirus Disease Covid 19 Ars Cov 2 Ngiotensin Converting Enzyme 2 Electron Microscopy

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Unique combination of nanomaterials in DNA biosensor enables easier SARS-CoV-2 detection

A recent paper that was published in the Talanta journal dedicated to original reports in pure and applied analytical chemistry presents for the first time the combination of two different nanomaterials โ€“ gold nanomaterials (AuNMs) and CDs for the development of an improved electrochemiluminescence (ECL) DNA biosensor.
Laura Guti Universidad Aut Coronavirus Disease Covid 19 Ars Cov 2 Covid 19 Electron Microscopy

Scientists provide a structural framework for Omicron immune evasion and ACE2 receptor recognition

An interesting preprint research paper describes structural changes resulting from the multiple mutations found in the recent Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is the causative agent behind the coronavirus disease 2019 (COVID-19) pandemic. In addition, the research describes the consequent effects of these changes on Omicronโ€™s infectivity and immune evasion capabilities.
United States Delta Vocs Beta Vocs Coronavirus Disease Covid 19 Ngiotensin Converting Enzyme 2 Binding Affinity

Study shows structural and functional aspects of antibody neutralization of SARS-CoV-2 Omicron variant

Researchers investigated the potency of trimeric human nephrocystin SH3, TriSb92, a domain-derived antibody, against a conserved region in the receptor-binding domain (RBD) of the spike protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern.
United States Aimee Molineux Neha Mathurdec Neha Mathur Drug Administration Image Credit

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