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Elsevier introduces authoritative scientific Datasets to fuel innovation in research-intensive industries

Elsevier, a global leader in scientific information and data analytics, has announced a new offering of enriched and authoritative scientific Datasets to power data applications that solve R&D challenges. Elsevier’s Datasets enable researchers, data scientists and practice leaders to answer R&D questions with greater speed and precision across many industries, including life sciences, energy, chemicals and materials, and technology.
Elsevier Datasets Gino Ussi Mark Sheehan Life Sciences Key Opinion Leader Corporate Markets

Researchers identify predictive brain imaging-based biomarkers of mental illness in adolescents

Research and treatment of psychiatric disorders are stymied by a lack of biomarkers - objective biological or physiological markers that can help diagnose, track, predict, and treat diseases.
Yihong Yang Brain Cognitive Development National Institute On Drug Abuse Neuroimaging Research Branch Biological Psychiatry Adolescent Brain Cognitive Development

Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal

Decades of previous efforts to develop renal-sparing polyene antifungals were misguided by the classic membrane permeabilization model1. Recently, the clinically vital but also highly renal-toxic small-molecule natural product amphotericin B was instead found to kill fungi primarily by forming extramembraneous sponge-like aggregates that extract ergosterol from lipid bilayers2–6. Here we show that rapid and selective extraction of fungal ergosterol can yield potent and renal-sparing polyen...
South Korea Fungal Priority Pathogens List To Guide Research Mcgraw Hill Laboratory Standards Institute Public Health Action World Organization Clinical Pharmacology
Source: nature.com

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