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3D printing crafts cerebral cortex tissues: A breakthrough for brain injury treatment

Researchers utilize 3D printing to craft cerebral cortex tissues with organized neurons, offering potential treatments for brain injuries. This novel technique prints neural progenitors in layer-by-layer sequences, aiming for accurate tissue restoration in damaged brains.
Neha Mathur Peter Porrini Shutterstock Sophia Coveney Neha Mathuroct Nature Communications Neural Maintenance Medium

Genetic markers could help women with rheumatoid arthritis make informed decisions about pregnancy

When women with rheumatoid arthritis (RA) plan to become pregnant, many anguish over whether to stop their medications, risking a flareup in their disease, or continue with medication and risk possible harm to the baby.
Danielle Ellis Damini Jawaheer Matthew Wright Juliane Marie Center National Institute Of Arthritis Northwestern University Feinberg School Of Medicine

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New study reveals alarming cardiovascular risks from COVID

The study published in Nature Cardiovascular Research reveals that SARS-CoV-2, the virus causing COVID-19, can directly infect coronary vessels and arterial plaques, heightening the risk of cardiovascular complications like heart attacks and strokes. These findings offer critical insights into the increased long-term cardiovascular risks for COVID-19 survivors and open new avenues for targeted therapies.
Nature Cardiovascular Research Changer For Heart Health Severe Acute Respiratory Syndrome Coronavirus Cardiovascular Threat Pathological Intimal Thickening Heart Health

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.
United States University Of Houston Texas Medical Center Megan Craig Frank Mckeon Department Of Chemistry

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Researchers have developed BigRNA, a groundbreaking deep learning model capable of predicting RNA behavior, including tissue-specific expression and splicing, directly from genomic DNA sequences. The model excels in identifying pathogenic variants and could be a game-changer in the development of personalized RNA-based therapies for treating genetic diseases.
Genotype Tissue Expression Whole Genome Sequencing Deep Learning Drug Discovery Ene Expression Machine Learning

Study details the key role played by neutrophils in ensuring survival of brain cancers

A Ludwig Cancer Research study has for the first time exhaustively analyzed immune cells known as neutrophils that reside in brain tumors, including gliomas, which develop in the brain itself, and cancers that spread there from the lung, breast and skin.
Ludwig Lausanne Johanna Joyce Johanna Joyce Danielle Ellis Ludwig Lausanne Roeltje Maas A Ludwig Cancer Research

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