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AI model accurately predicts which drugs may cause birth defects

Data scientists at the Icahn School of Medicine at Mount Sinai in New York and colleagues have created an artificial intelligence model that may more accurately predict which existing medicines, not currently classified as harmful, may in fact lead to congenital disabilities.
United States New York Lily Ramsey Avi Maayan Icahn School Of Medicine At Mount Sinai Pharmacological Sciences

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Berkeley Lab and Genentech collaborate to develop new lipid nanoparticles for drug delivery

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.
United States Apoorva Sarode Megan Craig Karthik Nagapudi Amye Byrnes Greg Hura

It takes three to tango: transcription factors bind DNA, protein, and RNA

Transcription factors are known to bind DNA and protein, but new research shows many of them also bind RNA. The work, from MIT and the Whitehead Institute for Biomedical Research, illuminates an aspect of gene expression and suggests new therapeutic opportunities.
Jonathan Henninger Ozgur Oksuz Richard Young Whitehead Institute For Biomedical Research Swiss Army Whitehead Institute
Source: mit.edu

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