Page 44 - Ene Expression News Today

In a recent study posted to the medRxiv* pre-print server, researchers demonstrated that two genes, GTPase, IMAP Family Member 7 (GIMAP7), and sphingosine-1-phosphate receptor 2 (S1PR2), have the potential to predict severe coronavirus disease 2019 (COVID-19) with ~90% accuracy.

Rheumatoid arthritis (RA) is characterized by chronic inflammation of synovium, eventually leading to joint destruction. Epigenetic alteration (the mechanism of gene expression regulation without DNA sequence changes), such as low levels of DNA methylation, is one of the factors which worsens the RA state.

A new study presents a novel approach to drug repurposing that incorporates two-stage prediction and machine learning.

In a recent study posted to the bioRxiv* preprint server, the authors demonstrated that the sarbecovirus pathogenesis was regulated by a multitrait locus.

A new study published in the journal Cell shows that a non-coding RNA molecule regulates mitochondrial gene expression in human cells.

Investigators at Cedars-Sinai have comprehensively mapped molecular activity in the brain and spinal cord that is responsible for regulating the body's response to central nervous system (CNS) disorders such as Alzheimer's, Huntington's disease and spinal cord injuries.

Researchers from the Icahn School of Medicine at Mount Sinai have applied a novel stem cell model to map disease risk variants in human neurons, which could help provide insights into the biological mechanisms that underlie neuropsychiatric disorders such as autism and schizophrenia.

Canola varieties exhibit variation in drought avoidance and drought escape traits, reflecting adaptation to water-deficit environments. Our understanding of underlying genes and their interaction across environments in improving crop productivity is limited. A doubled haploid population was analysed to identify quantitative trait loci (QTL) associated with water-use efficiency (WUE) related traits. High WUE in the vegetative phase was associated with low seed yield. Based on the resequenced pare...

Australian researchers have discovered the key immunological changes that support the remission of peanut allergy in children, paving the way for new, more targeted treatments.

Processes in the human body could turn groups of harmless immune cells into ruthless killers, capable of attacking other cells infected with viruses or parasites, and potentially tumor cells, a new study reveals.