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Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.
Emily Henderson Biosystems Dynamics Research Professor Toru Takumi Senior Visiting Scientist Researcher Chia Wen Lin Kobe University Graduate School

Cellular reprogramming can lead to better liver tissue regeneration in mice

Mammals can't typically regenerate organs as efficiently as other vertebrates, such as fish and lizards. Now, Salk scientists have found a way to partially reset liver cells to more youthful states-;allowing them to heal damaged tissue at a faster rate than previously observed.
Tomoaki Hishida Izpisua Belmonte Juan Carlos Izpisua Belmonte Emily Henderson Professor In Salk Gene Expression Laboratory Wakayama Medical University

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World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.
United States University Of California Riverside Aimee Molineux Aimee Molineuxapr Emanuel Charpentier Yanzstudio Shutterstock

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer's

A little-studied enzyme has been found in high levels in healthy neurons, levels that scientists say decline with age and more dramatically with Alzheimer's, making adjusting the enzyme's level a potential treatment for both.
United States Xin Yun Lu Neal Weintraub Emily Henderson Arizona Alzheimer Consortium Vascular Biology Center

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