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New computational approach creates spatial maps of single-cell data within tissues

A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution.
United States Nicholas Navin Runmin Wei Savitri Krishnamurthy Emily Henderson American Association For Cancer Research

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New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New research from Mayo Clinic's Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia -; an uncommon type of cancer of the bone marrow -; have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster.
Moritz Binder Emily Henderson Nature Communications Gerstner Family Career Development Mayo Clinic Center Mayo Clinic

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Researchers reported the association of a single nucleotide polymorphism rs9984273 in the interferon-alpha/beta receptor gene with outcomes of acute respiratory distress syndrome and COVID-19.
Ras Association Domain Family Member Chronic Health Evaluation Host Genetics Initiative Minichromosome Maintenance Complex Component Acute Physiology Genetics Initiative

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