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New study uncovers how altered gene expressio

<p><strong>The loss-of-function mutation of <em>KMT2C</em>, a gene involved in histone modification, leads to the development of autism and other neurodevelopmental deficits. However, the precise mechanism of the disease progression is still unknown. Now, researchers from Japan have developed an animal model and elucidated the mechanism by which mutation in genes involved in chromatin modification causes autism. They have also discovered a drug that can be used in the tre...
Japan General Shigehiro Kuraku Tadafumi Kato Kurara Honda Takumi Nakamura Atsushi Takata

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The genomic architecture of inherited DNA var

<p>In a study that spans more than a decade, researchers at Baylor College of Medicine have looked at generations of families in a specific population to reveal the role newly inherited DNA variants play on recessive disease traits, and in the process, they have created a population specific database revealing unique DNA information unseen in larger cohorts.</p>
United States Baylor College Of Medicine Franciscoc Ceballos Salud Carlos Claudia Mb Carvalho Eric Boerwinkle

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