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Novel Oral Agent Possible 'Major Advance' in von Hippel-Lindau Disease Tx

Belzutifan might serve as an alternative for or a complement to surgery Belzutifan (MK-6482), a novel oral agent that targets germline pathogenic variants in the von Hippel-Lindau (VHL) gene that gives rise to VHL disease, demonstrated robust clinical activity and a very mild adverse event (AE) profile in VHL patients with renal cell carcinoma, a
United States Ppam Harrison Eric Jonasch Manuela Schmidinger Novartis Pharma Exelixis Inc

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FDA Approves Merck's Hypoxia-Inducible Factor-2 Alpha Inhibitor WELIREG for the Treatment of Patients With Certain Types of Von Hippel-Lindau Disease-Associated Tumors

WELIREG Approved for Adult Patients With VHL Disease Who Require Therapy for Associated Renal Cell Carcinoma, Central Nervous System Hemangioblastomas, or Pancreatic Neuroendocrine Tumors, Not Requiring Immediate Surgery WELIREG Expands Merck’s Oncology Portfolio as the First and Only Systemic Therapy Approved for These Patients With VHL Disease Merck known as MSD outside the United States and Canada, today ...
United States Scot Ebbinghaus Ramaprasad Srinivasan Peter Dannenbaum Eric Jonasch Melissa Moody

JNCCN Study: Important Potential Role for Routine Brain Imaging in Advanced Kidney Cancer

Share this article PLYMOUTH MEETING, Pa., April 13, 2021 /PRNewswire/ -- The April 2021 issue of JNCCN—Journal of the National Comprehensive Cancer Network publishes new research from Memorial Sloan Kettering Cancer Center (MSK) and Gustave Roussy Institute, which suggests that baseline brain imaging should be considered in most patients with metastatic kidney cancer. The researchers studied 1,689 patients with metastatic renal cell carcinoma (mRCC) who had been considered for clinical tria...
United States France General Rachel Darwin Riteshr Kotecha Martinh Voss Facebook Nccnorg

2021 Research Grant Recipients Announced by the VHL Alliance

2021 Research Grant Recipients Announced by the VHL Alliance Global Research Program Supports Curing Cancer through VHL News provided by Share this article Share this article BOSTON, Jan. 19, 2021 /PRNewswire/ -- The VHL Alliance (VHLA) today announced the 2021 recipients of the VHLA Competitive Research Grant Program.  This year, three grantees were chosen. Scientists are increasingly aware that curing von Hippel-Lindau disease, a genetic form of cancer – is a key step to curing cancer, le...
New York United States Tel Aviv Amit Tirosh David Zagzag Chandra Clark

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