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Exploring a human multi-organ microphysiological system for preclinical oral bioavailability profiling

Exploring a human multi-organ microphysiological system for preclinical oral bioavailability profiling
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Physiomimix-dualorgan
Aimee-molineux
Scott-magness
Altis-biosystems
European-journal-of-pharmaceutical-sciences
A-assembly-of-the-physiomimix-system
Sponsored-content
Multi-organ-system
Expression-assays
Physiomimix-dual-organ
Physiomimix-multi-organ-system
Multi-chip-dual-organ

Novel Research Shows Promise for Tuberculosis Treatment Innovation

Tuberculosis (TB) is the world’s deadliest bacterial disease and most commonly affects the lungs. Recent years have seen an increase in drug-resistant TB cases leaving many patients with limited treatment options. The only vaccine - BCG - is relative

Dublin
Ireland
Joseph-keane
Ahmad-bahlool
Sally-ann-cryan
Mary-osullivan
Health-sciences
European-journal-of-pharmaceutical-sciences
Trinity-college-dublin
Trinity-translational-medicine-institute
University-of-medicine
School-of-pharmacy-biomolecular-sciences

Researchers propose host-directed therapy to stimulate immune system to eliminate tuberculosis

Researchers propose host-directed therapy to stimulate immune system to eliminate tuberculosis
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Dublin
Ireland
Ahmad-bahlool
Sally-ann-cryan
Ahmadz-bahlool
Joseph-keane
Mary-osullivan
Trinity-translational-medicine-institute
Tb-immunology-research-group
Trinity-college-dublin
School-of-pharmacy-biomolecular-sciences
Trinity-college

CN Bio and Altis Biosystems Partner to Develop Next-generation Human Gut/Liver in vitro model for Advanced ADME Studies

CN Bio and Altis Biosystems Partner to Develop Next-generation Human Gut/Liver in vitro model for Advanced ADME Studies
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Yassen-abbas
Lily-jeffery
Ben-scruggs
Altis-biosystems
Stefan-klotter
Bio-physiomimix
Cn-bio-contract-research-services
European-journal-of-pharmaceutical-sciences
Altis-biosystems-inc
Contract-research-services
Repligut-planar
Gut-planar

DASYNOC™ Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL® Uptake is Significantly More Impaired than Previously Understood

DASYNOC™ Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL® Uptake is Significantly More Impaired than Previously Understood
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Charlotte-wray
Kerstin-hasselgren
Bristol-myers-squibb
European-journal-of-pharmaceutical-sciences
Drug-administration
Per-anderson
Pharmacodynamic-biomarkers
Animal-models-predict-optimal-clinical
H-dependent-solubility
Achilles-heel
Clin-pharmacol-ther
Gastrointestinal-simulator

Xspray Pharma AB: DASYNOC Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL Uptake is Significantly More Impaired than Previously Understood

Xspray Pharma AB: DASYNOC Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL Uptake is Significantly More Impaired than Previously Understood
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Charlotte-wray
Kerstin-hasselgren
Bristol-myers-squibb
European-journal-of-pharmaceutical-sciences
Hynap-technology
Drug-administration
Per-anderson
Pharmacodynamic-biomarkers
Animal-models-predict-optimal-clinical
H-dependent-solubility
Achilles-heel

DASYNOC™ Uptake into the Blood Remains Consistent When Taken with Omeprazole, Whereas SPRYCEL® Uptak

 DASYNOC (Xspray’s low dose, amorphous, non-crystalline, dasatinib) avoids interactions with proton pump inhibitors (PPIs), making it potentially the first and only dasatinib to provide patients the full therapeutic benefit of their treatmentSPRYCEL (crystalline dasatinib) uptake, when used with omeprazole, provides...

Charlotte-wray
Kerstin-hasselgren
Bristol-myers-squibb
European-journal-of-pharmaceutical-sciences
Drug-administration
Xspray-pharma
Per-anderson
Pharmacodynamic-biomarkers
Animal-models-predict-optimal-clinical
H-dependent-solubility
Achilles-heel
Clin-pharmacol-ther

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