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Enzalutamide Maintains HRQoL in High-Risk Recurrent nmCSPC - Renal and Urology News

Multiple surveys of patient-reported outcomes from the phase 3 EMBARK trial revealed no meaningful differences in pain progression or urinary symptoms and bowel symptoms or function over 205 weeks of follow-up. Enzalutamide does not worsen health-related quality of life compared with androgen deprivation therapy in patients with high-risk biochemically recurrence nmCSPC.

Chemotherapy-Related Amenorrhea Common Among Younger Breast Cancer Survivors

Type of therapy, use of endocrine therapy, age at diagnosis, and other symptoms influenced the likelihood of CRA in breast cancer survivors.

FDA Approves Capivasertib Plus Fulvestrant in Advanced HR+/HER2– Breast Cancer With PIK3CA, AKT1, or PTEN Alterations

The FDA has approved capivasertib plus fulvestrant for the treatment of patients with HR-positive, HER2-negative, locally advanced or metastatic breast cancer harboring 1 or more PIK3CA, AKT1, or PTEN alteration, following progression on at least 1 endocrine-based regimen in the metastatic setting or recurrence on or within 12 months of completing adjuvant therapy.

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