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Obesity, High BMI Linked to Greater MS Risk, Autoimmune Activity

Obesity, High BMI Linked to Greater MS Risk, Autoimmune Activity 3.7 (21) Obesity and a higher body mass index (BMI) are associated with both increased multiple sclerosis (MS) risk and harmful autoimmune activity that is induced by leptin, a hormone secreted by fat cells, a study finds. These results indicate that leptin, which helps regulate body weight, may act as a functional link between obesity and MS. The worldwide prevalence of MS has increased over the past years, ...
Faisha Abdullah Leiden University Medical Center World Health Organization Weill Cornell Medical College University Of Houston Medical Microbiology

Stem Cell Treatment Reduced Disability in Some Progressive MS Patients

MSC-NPs are seen as a possible way of treating people with progressive MS, who have few effective disease-modifying treatments available. They are essentially stem cells collected from a patient’s bone marrow that are expanded and matured to produce factors involved in modulating the immune response and in nervous tissue growth and survival. An open-label Phase 1 trial (NCT01933802) investigated this stem cell treatment  in 20 adults with stable primary (four PPMS patients) or secondary ...
New York United States Faisha Abdullah University Of Lisbon Weill Cornell Medical College Biomedical Sciences

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