Abu Dhabi: New York University Abu Dhabi (NYUAD) and New York University (NYU) have created a ‘developmental atlas’ of gene expression in neurons, using gene sequencing and machine learning to categorise more than 250,000 neurons in the brains of fruit flies.
The study, published in ‘Nature’, a leading multidisciplinary science journal, finds that neurons exhibit the most molecular diversity during development and reveals a previously unknown type of neurons only present before flies hatch.
Speaking about the discovery, Desplan, the study’s senior author, commented: “Although most efforts to define the diversity of the human or mouse brain focus on adult neurons, our work shows that the diversity of the different cell types that make up our brains can only be fully understood in light of their developmental history.”
Biologists create ‘Atlas’ of gene expression in neurons, documenting diversity of brain cells December 20, 2020
A team of researchers from NYU Abu Dhabi (NYUAD) and New York University (NYU) has created a developmental atlas of gene expression in neurons, using gene sequencing and machine learning to categorize more than 250,000 neurons in the brains of fruit flies.
ABU DHABI A team of researchers from NYU Abu Dhabi (NYUAD) and New York University (NYU) has created a developmental atlas of gene expression in neurons, using gene sequencing and machine learning to categorize more than 250,000 neurons in the brains of fruit flies.
The study led by Claude Desplan, silver professor of Biology and of Neuroscience at NYU and co-director of NYUAD’s Centre for Genomics and Systems Biology (CGSB), has been published in Nature, the world’s leading multidisciplinary science journal.