A spatially resolved timeline of the human maternal–fetal interface
Beginning in the first trimester, fetally derived extravillous trophoblasts (EVTs) invade the uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels. Several mechanisms have been proposed to explain how EVTs coordinate with the maternal decidua to promote a tissue microenvironment conducive to spiral artery remodelling (SAR)1–3. However, it remains a matter of debate regarding which immune and stromal cells participate in these interactions and how this...
Leica Biosystems Dako Agilent Nanostring Geomx Flowsom Bioconductor Flow Perivascular Evts Electron Microscopy Sciences
Source: nature.com