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SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models

Science for just $15 USD. Short circuiting solid tumors Two major hurdles in chimeric antigen receptor (CAR) T cell therapy for solid tumors are ensuring specificity to tumor cells without affecting healthy cells and avoiding tumor escape due to antigen loss. To address these challenges, Hyrenius-Wittsten et al. and Choe et al. developed synthetic Notch (synNotch)–CAR T cells targeting solid tumor antigens and used them to treat mouse models of mesothelioma, ovarian cancer, and glioblastoma...
United Kingdom Takara Bio Facsaria Iiiu Chan Zuckerberg Biohub Celltrace Violet B Ebert Addgene

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Xerox Reveals Suite of Production Print Innovations to Address Industry Demand

Technuter At a virtual event attended by partners and clients around the world, Xerox unveiled the following innovations: AĀ  Color Accelerator moduleĀ for Baltoro, expanding inkjetĀ applications and adding ink-saving automation Addition of fluorescent pinkĀ to the Iridesse Production Press, enhancing its metallics, white and clear color palette Two new printersĀ capable of higher volumes, more media and extended color options in the Versant family Two Xerox NuveraĀ  AI-enabled media manager so...
Vineet Gehani Xerox Baltoro High Fusion Inkjet Iridesse Production Hf Inkjet Color Accelerator Iridesse Production Press

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