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### What you need to know Upper respiratory tract infections (URTIs) are common, self-limiting illnesses that are distressing for children and families.123 Despite the large number of treatments marketed for relief of cough and common cold symptoms, the evidence for their efficacy is of poor quality with high risk of bias. Most studies find no evidence of benefit in reducing nasal symptoms and cough, and several treatments have serious risk of harm. Clinicians and healthcare practitioners can discuss with families how coughs and colds develop, can provide reassurance and safety netting advice, and discuss the pros and cons of treatments that are safe and may offer some symptomatic benefit. This practice pointer aims to describe commonly used cough and common cold therapies in children (aged 12 and under), including the data on their safety and effectiveness, and to provide recommendations for practitioners and parents on how to manage bothersome symptoms and reduce the use of inapprop

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