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Olaparib regimen benefits men with metastatic castration-resistant prostate cancer

SAN FRANCISCO  — The addition of olaparib to abiraterone acetate significantly extended radiographic PFS as first-line treatment for metastatic castration-resistant prostate cancer, according to an interim analysis of the randomized phase 3 PROpel study. The findings, presented at ASCO Genitourinary Cancers Symposium, showed men experienced the benefit regardless of homologous
San Francisco United States Devin Mclaughlin Fred Saad Astellas Pharma Myovant Sciences
Source: healio.com

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Preoperative Frailty Predicts Adverse Short-Term Postoperative Outcomes in Patients Treated with Radical Prostatectomy

Published 19 January 2021 Background - To investigate the effect of frailty on short-term postoperative outcomes in patients with prostate cancer treated with radical prostatectomy (RP). Methods - Within the National Inpatient Sample database, we identified 91,618 RP patients treated between 2008 and 2015. The Johns Hopkins Adjusted Clinical Groups frailty-defining indicator was applied, and we examined the rates of frailty over time, as well as its effect on overall complications, major comp...
Permskiy Kray Nordrhein Westfalen United States Giorgio Gandaglia Fred Saad Lond Engl

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