Page 2 - Frontier Program News Today

Researchers at Childrens Hospital of Philadelphia (CHOP) have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and adult hemoglobin. Using a viral vector engineered to reactivate fetal hemoglobin production, suppress mutant hemoglobin, and supply functional adult hemoglobin, the researchers developed an approach that could produce more hemoglobin through a single vect...

/PRNewswire/ -- Researchers at Childrens Hospital of Philadelphia (CHOP) have developed a proof-of-concept treatment for blood disorders like sickle cell...

Date Time Less is More for Next Generation of CAR T Cells PHILADELPHIA—When researchers from Penn Medicine found that many patients with B-cell acute lymphoblastic leukemia (ALL) treated with the investigational chimeric antigen receptor (CAR) T cell therapy targeting the CD22 antigen didn’t respond, they went back to the drawing board to determine why. They discovered that less is more when it comes to the length of what is known as the single-chain variable fragment — the linker that br...

Date Time Researchers Develop Potentially Safer, More Effective Gene Therapy Vector for Blood Disorders Researchers at Children’s Hospital of Philadelphia (CHOP) have developed a gene therapy vector for blood disorders like sickle cell disease and beta-thalassemia that is potentially safer and more effective than those currently used in gene therapy trials for those conditions. The vector, an engineered vehicle for delivering functional copies of the hemoglobin gene to correct a genetic abnor...

 E-Mail Philadelphia, January 29, 2021--Researchers at Childrens Hospital of Philadelphia (CHOP) have developed a gene therapy vector for blood disorders like sickle cell disease and beta-thalassemia that is potentially safer and more effective than those currently used in gene therapy trials for those conditions. The vector, an engineered vehicle for delivering functional copies of the hemoglobin gene to correct a genetic abnormality, leads to the production of more hemoglobin with a lower do...

CHOP Researchers Develop Potentially Safer, More Effective Gene Therapy Vector for Blood Disorders --New preclinical study shows vector results in significantly more hemoglobin production than vectors currently used in gene therapy for sickle cell disease and beta-thalassemia-- News provided by Share this article Share this article PHILADELPHIA, Jan. 29, 2021 /PRNewswire/ -- Researchers at Childrens Hospital of Philadelphia (CHOP) have developed a gene therapy vector for blood disorders like s...

This year there’s a scaled-down selection of titles to view, with Baobab Studios’ Namoo is Korean for “tree”, taking viewers on a journey through a man’s life with each branch a different memory. Created using Oculus’  Quill,the project will be coming to Oculus platforms later this year. And then there’s Prison X, Chapter 1: The Devil and The Sun, a new VR series from Quechua filmmaker Violeta Ayala. The first episode takes you into Bolivia’s infamous San Sebastian Prison...

There’s more than 1 way to send a spacecraft to Venus A look at Rocket Lab’s private mission to Earth’s twin, and how NASA decides what planets to visit Updated:  Tags:  NASA last sent a spacecraft to orbit Earth’s nearest neighbor in 1990. Russia, formerly the Soviet Union, sent a whole slew of mostly successful missions to Venus, and Japan has an orbiter there now. The tricky part is sending a robotic mission to the surface. Most have only survived for a few hours. So why send a rob...

We have esther arms, bob franklin, robert costa. we left off with you, robert. we have 77 cents on the dollar in 2012. does this affect those of color more than those who are not? >> it is really distressing if those are the statistics. this was past in 1963, part of jfks new frontier program. 50 years on, it is clear there are some problems remaining in the work place. you think congress is paying attention. you hope they are. i think it is something we all should be paying attention to as the ...