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Osimertinib Plus Chemo Improves CNS PFS in EGFR+ Advanced NSCLC With Baseline Brain Metastases

Osimertinib plus chemotherapy reduced the risk of central nervous system disease progression or death vs osimertinib alone in patients with locally advanced or metastatic EGFR-positive non–small cell lung cancer who had brain metastases at baseline, according to data from the phase 3 FLAURA2 trial.
France General Institut Gustave Roussy David Planchard Osimertinib Tagrisso Common Terminology Criteria Adverse Events

Tagrisso-Chemo Combo Reduces Progression Risk in EGFR-Positive NSCLC With Central Nervous System Metastases

Treating patients with Tagrisso, a tyrosine kinase inhibitor, plus chemotherapy reduced the progression risk of disease of the central nervous system in patients with EGFR-positive non-small cell lung cancer.
France General Institut Gustave Roussy David Planchard European Society For Medical Oncology Congress Medical Oncology Full Analysis

Akero Therapeutics Reports Encouraging 36-Week Analysis of 96-Week Phase 2b SYMMETRY Study, with a Trend on Fibrosis Improvement and Statistically Significant Results for NASH Resolution, Markers of Liver Injury and Fibrosis, Insulin Sensitization and Lipoproteins

22% and 24% of patients experienced at least a one-stage improvement in liver fibrosis with no worsening of NASH by week 36, compared to 14% for placebo 4% of patients in each EFX dose group...
United States Sarah Oconnell Andrew Cheng Pa Fibroscan Stephen Harrison Austin Murtagh

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Trevi Therapeutics Reports Statistically Significant Result on Interim Analysis from the Ph2 CANAL Trial of Nalbuphine ER in the Treatment of Chronic Cough in Idiopathic Pulmonary Fibrosis

/PRNewswire/ -- Trevi Therapeutics, Inc. (Nasdaq: TRVI) today announced positive interim analysis results of the Phase 2 Cough And NALbuphine (CANAL) trial of...
United States United Kingdom Rosalia Scampoli Katie Mcmanus Toby Maher Exchange Commission

Supreme Court Rules Ban on Indoor Worship Services in L.A. is Unconstitutional – Soldier of Fortune Magazine

20A137 HARVEST ROCK CHURCH, ET AL. V. NEWSOM, GOV. OF CA The application for injunctive relief presented to Justice Kagan and by her referred to the Court is granted in part. Respondent is enjoined from enforcing the Blueprint’s Tier 1 prohibition on indoor worship services against the applicants pending disposition of the appeal in the United States Court of Appeals for the Ninth Circuit and disposition of the petition for a writ of certiorari, if such writ is timely sought. The application ...
United States San Diego Justice Sotomayor Justice Kagan Justice Breyer Justice Alito
Source: sofmag.com

EMEA Emerging Market Sovereign Rating Trends 2021

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Burkina Faso United Kingdom Ras Al Khaimah Ras Al Khaymah United Arab Emirates Cabo Delgado

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