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Investigating a role for complement in gene therapy

Immunology expert discusses the complement system, immunogenicity challenges in AAV-mediated gene therapy, and more

Klaudia kurandaAnna majowiczTechnology department at spark therapeuticsTechnology departmentEditorial articleSpark therapeuticsPreclinical immunology leadSvar life scienceFunctional complement assaysComplement systemComplement system alternative pathwayComplement system classicalThe importance of investigating complement system in gene therapy selectscience aavAv gene therapyOmplement activiationAv capsid specifict cells

Complement system could provide cancer prognostic biomarkers

Context-dependent role of complement in cancer could provide novel prognostic biomarkers to inform treatment decisions

France generalFridman wh context dependentLubka roumeninaCordeliers research centerCancer teamFrench national institute of healthEditorial articleSenior scientistFrench national instituteMedical researchDeputy directorCordeliers researchComplement biomarker assaysFunctional complement assaysSvar life scienceSvar life

Complement system could provide cancer prognostic biomarkers

Context-dependent role of complement in cancer could provide novel prognostic biomarkers to inform treatment decisions

France generalFridman wh context dependentLubka roumeninaCancer teamCordeliers research centerFrench national institute of healthEditorial articleSenior scientistFrench national instituteMedical researchDeputy directorCordeliers researchComplement biomarker assaysFunctional complement assaysSvar life scienceSvar life

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