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Study linking mucus plugs and COPD mortality

Many patients with chronic obstructive pulmonary disease (COPD) experience airway-clogging mucus plugs, an accumulation of mucus in the lungs that can affect quality of life and lung functioning. A new study led by researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, has found that mucus plugs were also associated with greater mortality. The findings, published in JAMA and presented simultaneously at the American Thoracic Society 2023...
United States Meilank Han Victor Kim Georger Washko Alejandroa Diaz American Thoracic Society

Glasgow prognostic score may predict survival in small cell lung cancer

Glasgow prognostic score appeared associated with survival among patients with small cell lung cancer treated with first-line atezolizumab plus carboplatin and etoposide, according to study results.No biomarkers are available to predict effectiveness of first-line therapy with atezolizumab (Tecentriq, Genentech) — an anti-PD-L1 antibody — plus carboplatin and etoposide for patients
Mindy Valcarcel Satoshi Wasamoto Bymark Leiser Hospital Advanced Care Center Saku General Hospital Advanced Care Center
Source: healio.com

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AEGEAN Trial Demonstrates Benefit and Viability of Novel Perioperative Treatment Approach in NSCLC

John V. Heymach, MD, PhD, expands on the efficacy of perioperative durvalumab in the AEGAN trial, the significance of this unique approach for the non–small cell lung cancer treatment paradigm, and future research examining opportunities to build on or intensify the benefit achieved with this regimen.
United States Johnv Heymach Chugai Pharmaceuticals Eli Lilly Co Cancer Research Bristol Myers Squibb

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