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Triplet therapy effective for metastatic prostate cancer subset regardless of disease volume

Treatment intensification with darolutamide plus androgen deprivation therapy and docetaxel improved OS among men with metastatic hormone-sensitive prostate cancer regardless of disease volume or risk, according to study results.The benefits of early treatment intensification appeared consistent among men with high-volume or low-volume disease, as well as those with high-risk or low-risk disease,
Byashley Killen Mark Leiser Maha Ha Hussain Astellas Pharma Cancers Symposium Clinical Oncology
Source: healio.com

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Patients with ANCA-associated vasculitis remain 'soaked in steroids' despite new therapies

DESTIN, Fla. — Despite advances in biologic therapies, “excess steroid use” remains a mainstay of treatment for patients with ANCA-associated vasculitis,” according to a presenter at the 2023 Congress of Clinical Rheumatology-East.
United States Byrob Volansky John Stone Shenaz Bagha Edwarda Fox Harvard Medical School
Source: healio.com

F. Hoffmann-La Roche Ltd: Roche launches Institute of Human Biology to accelerate breakthroughs in R&D by unlocking the potential of human model systems

The Institute of Human Biology aims to better predict which drug candidates are safe and most effective in patients by evolving and increasing the use of human model systems. Human model systems are miniature
United States Gerard Tobin Hans Clevers Bruno Eschli Loren Kalm Kirti Pandey

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