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Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.
United States Mahammad Gardashli Maria Ulloa Navas Kyriaktisa Galani Myriam Heiman Andre Hucke

Researchers create new platform to identify proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease.
Mikko Taipale Sinai Health Biomolecular Research University Of Toronto Donnelly Centre Donnelly Centre For Cellular

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