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MSD and AstraZeneca announce phase 3 results for prostate cancer therapy

MSD and AstraZeneca announce phase 3 results for prostate cancer therapy
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PROpel Phase III trial positive results of Lynparza plus abiraterone in 1st-line metastatic castration-resistant prostate cancer published in New England Journal of Medicine Evidence

Results from the PROpel Phase III trial showed that AstraZeneca and MSD’s Lynparza (olaparib) in combination with abiraterone significantly improved radiographic progression-free survival (rPFS) versus abiraterone alone as a 1st-line treatment for patients with metastatic castration-resistant prostate cancer .

United kingdomUnited statesNoel clarkeEliav barrCristian massacesiCompany on twitterAmerican society of clinical oncologyInternational journal of clinical practiceUniversity of manchesterData monitoring committeeMerck co incResearch laboratoriesInvestor relations teamHead of global clinical developmentNew england journalNeurological surgeon

Results From Phase 3 PROpel Trial of LYNPARZA (olaparib) Plus Abiraterone in First-Line Metastatic Castration-Resistant Prostate Cancer Published in NEJM Evidence

21.06.2022 - AstraZeneca and Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the results from the Phase 3 PROpel trial have been published in NEJM Evidence. Results from the trial showed that LYNPARZA in combination .

United statesNoel clarkeEliav barrCristian massacesiMerck research laboratoriesAmerican society of clinical oncologyUniversity of manchesterData monitoring committeeStatement of merck co incMerck co incExchange commissionEuropean unionSalford royal hospitalsClinical oncologyGenitourinary cancers symposiumAcute myeloid leukemia

ASCO Reading Room | Carlos Riveros, MD, on Impact of Fragmented Care on Muscle-Invasive Bladder Care

In muscle-invasive bladder cancer (MIBC), the with neoadjuvant chemotherapy followed by radical cystectomy is often delivered at a single facility that provides integrated care. In some cases, however, care can be more , with chemotherapy delivered at one facility and surgery at another.

United statesCarlos riverosNational cancer databaseDepartment of urologyUniversity of florida uf health jacksonvilleHealth jacksonvilleNational cancerGenitourinary cancers symposiumClin oncol

Advancing Bladder Cancer Treatment by Studying Biomarkers Ability to Respond to Chemotherapy

Advancing Bladder Cancer Treatment by Studying Biomarkers Ability to Respond to Chemotherapy
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United statesSan franciscoThomas flaigAmerican society of clinical oncologyMedical campusAmerican societyClinical oncologyGenitourinary cancers symposium