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Gift from Schmidt Futures to spark a revolution in AI-based STEM research at the University of Toronto

With the goal of accelerating scientific research through the application of artificial intelligence, Schmidt Futures is investing $148-million in nine global universities, including the University of Toronto.

Eric schmidtLeah cowenMeric gertlerWendy schmidtGoogle industrial researchDalla lana school of public healthUniversity of torontoCanada researchCanadian statistical sciences instituteT data sciences instituteT acceleration consortiumVector institute for artificial intelligenceSchmidt futuresScience postdoctoral fellowshipScience postdocsStu feldman

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

CRISPR/Cas9 is a commonly used, very precise, gene editing technique whose development, by Jennifer A. Doudna and Emmanuelle Charpentier, was recognised with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors", CRISPR allows the introduction of the desired DNA sequence into (virtually) any spot of the genome, thus modifying or inactivating a gene. This technique is widely used in biomedical research and some CRISPR-based therapies are in clinical trials for the treatment of human blood disorders, some types of cancer and HIV, among other conditions.

Comunidad autonoma de catalunaFran supekEmmanuelle charpentierJennifera doudnaEmily hendersonNature communicationsInstitute for researchGenome data scienceDna damage

Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability

Gene editing via CRISPR/Cas9 can lead to cell toxicity and genome instability

Comunidad autonoma de catalunaFran supekJosep biayna fran supekEmmanuelle charpentierJennifera doudnaNature communicationsSpanish ministry of scienceEuropean research councilGenome data scienceEuropean researchSpanish ministryJosep biaynaCrispr cas9Protein p53

Study: CRISPR gene editing can lead to cell toxicity and genome instability

Scientists at IRB Barcelona say CRISPR gene editing can give rise to cell toxicity and genomic instability.

Comunidad autonoma de catalunaFran supekNature communicationsGenome data science

Not individual genes but mutational signatures of many genes hold key to better cancer therapies

Not individual genes but mutational signatures of many genes hold key to better cancer therapies
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Comunidad autonoma de catalunaJurica levatiMarie curieMarina salvadoresFran supekSpanish ministry of scienceJozef stefan instituteGenome data scienceSpanish ministry

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