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Unhealthy vaginal microbiome in mothers may contribute to infant deaths and altered development

A new study in mice from University of Maryland School of Medicine researchers showed that an unhealthy vaginal microbiome in pregnant mothers in combination with an unhealthy diet contributed to increased pup deaths and altered development in the surviving babies.
Akikok Bowers E Albert Reece Jacques Ravel Emily Henderson Nature Communications Epigenetic Research In Child Health Brain Development

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CWRU, Ionis Pharmaceuticals sign exclusive license agreement to advance therapy for rare childhood disorder

Principal investigator Paul Tesar, of Case Western Reserve University, said the agreement is 'a major step toward a transformational antisense medicine' for patients with Pelizaeus-Merzbacher disease, a rare childhood degenerative disorder of the central nervous system in which coordination, motor abilities and intellectual function progressively deteriorate.
United States C Frank Bennett Ruth Weber Goodman Paul Tesar Case Western Reserve School Of Medicine Technology Transfer Office

FANCI: a new gene at the origin of some cases of ovarian cancer | McGill University Health Centre

Researchers link for the first time mutations in the FANCI gene to the risk of developing ovarian cancerย  Montreal -ย Ovarian cancer affects approximately 3000 women per year in Canada. Although most cases are sporadic, there are hereditary forms of ovarian cancer that are largely attributed to mutations in the BRCA1 and BRCA2 genes, which are also involved in breast cancer. However, some families with no known cancer predisposing genes develop multiple cases of ovarian cancer, suggesting that ...
Fierheller Caitlin Caitlint Fierheller Deepakn Subramanian Caitlin Fierheller Jacek Majewski Wejdanm Alenezi
Source: muhc.ca

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