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Sagimet Biosciences Appoints Life Sciences Industry Veteran Elizabeth Grammer to Board of Directors
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SAN MATEO, Calif., May 3, 2021 /PRNewswire/ -- Sagimet Biosciences, a clinical-stage biotechnology company focused on developing a portfolio of internally-discovered, selective fatty acid synthase (FASN) inhibitors, announced today the appointment of Elizabeth Grammer, Esq., to its board of directors. Ms. Grammer brings to her role as director over 25 years of experience advising privately held and publicly traded life sciences companies at all stages of development.
George Kemble, Ph.D., Sagimet's chief executive officer, said, "Elizabeth is a strategic and innovative thinker with a passion for developing, articulating and leading the execution of corporate strategy and will be a great addition to our board. We look forward to leveraging her extensive experience to help Sagimet grow our business."
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SAN MATEO, Calif., March 16, 2021 /PRNewswire/ -- Sagimet Biosciences Inc., a clinical-stage biotechnology company focused on developing a portfolio of internally-discovered, selective fatty acid synthase (FASN) inhibitors, announced today that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to TVB-2640 for the treatment of patients with NASH.
TVB-2640, is a wholly-owned, oral, selective inhibitor of FASN, a key enzyme involved in the production of saturated fatty acids in the liver and other organs, and is the only enzyme in the human body capable of converting metabolized sugars into palmitate. In patients with NASH, increased FASN-mediated palmitate synthesis in the liver is the source of three key drivers of the disease: excess accumulation of liver fat, inflammation and fibrosis.
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