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CAR T-Cell Therapy for Solid Tumors Gets Boost from Cytokine Receptors

Enhanced CAR T-Cell Therapy Targets Solid Tumors with New Receptors

Modular chimeric cytokine receptors improve CAR T-cell therapy for solid tumors

'Special' CAR-T target works in solid tumors, but limits remain

St. Jude scientists discover potential CAR T cell therapy target for brain and solid tumors

Findings from St. Jude Children's Research Hospital are moving the field of cancer immunotherapy one step closer to treating brain and solid tumors.

Promising target for CAR T cells helps cancer trick the immune system

Gottschalk and Krenciute Discuss the Development of CAR T-cell Therapy in Pediatric Solid Tumors

Drs Gottschalk and Krenciute discuss the difficulties of translating successes with CAR T-cell therapy in adults to the pediatric population; ongoing research with investigational products that could reduce T-cell exhaustion, burnout, and the time from bench to bedside; and expectations for the future of cellular therapy in oncology.

Improving CAR-based-immunotherapies using a molecular anchor

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective.

St. Jude Scientists Create More Efficient CAR Immunotherapies

Giving Immunotherapy Cells Resilience to Pass the 'Stress Test'

T cells used in immunotherapy treatments can get exhausted and shut down by fighting cancer cells and tumors. Using a CRISPR-based edit on these cells’ genomes, researchers at UCSF and Gladstone Institutes have rendered the therapeutic cells more resilient against tumors.