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In Science Journals

In Science Journals
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Rethinking How Cancer Cells Evade Targeted Therapy

Rethinking How Cancer Cells Evade Targeted Therapy
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Phenotypic plasticity may allow cancer cells to evade standard therapy

Glioblastomas (GBMs) are incurable brain tumors with a prognosis of about one-and-a half years on average. They are highly resistant to treatment and have defied all attempts at precision therapy.

Exploring Strategies to Combat Cancer Cell Resistance

Exploring Strategies to Combat Cancer Cell Resistance
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Using off-the-shelf engineered stem cell based therapy for treating glioblastomas post-surgery

Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most successful way to treat the disease.

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