Key mutation sites in the SARS-CoV-2 spike protein modulate antibody and ACE2 affinity
Key mutation sites in the SARS-CoV-2 spike protein modulate antibody and ACE2 affinity An allosteric center or site is one where a molecule other than the substrate to the protein can bind, altering the conformation of the protein. A paper recently uploaded to the preprint server bioRxiv* by researchers at Chapman University in California (Feb 22nd, 2021) utilized computational methods to screen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutants for affinity with the angioten...
Source: news-medical.net