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Tocilizumab Withdrawal Post Remission in Still s Disease

Longer tocilizumab administration intervals and lower prednisolone doses seemed pivotal for successful tocilizumab withdrawal while maintaining remission in patients with AOSD.

Hiroya tamaiDivision of rheumatologyDepartment of internal medicineKeio university school of medicineInternal medicineKeio university schoolBiologic therapyJuvenile rheumatoid arthritisUvenile raJuvenile idiopathic arthritisGlucocorticoid therapyAttending physician

Cushing Remission After Surgery May Raise Autoimmune Risk

The findings suggested the need for closer postsurgical monitoring of patients with a family history of autoimmune disease.

United statesLos angelesAnthonyp heaneyDennis delasi nyanyoHarvard medical schoolUniversity of californiaMassachusetts general hospitalPatients with family historyPostoperative adrenal insufficiency contributeCushing amp 039s syndromeUshing amp 039s diseaseCushing syndromeCushing diseaseAutoimmune diseaseThyroid disorderThyroid disease

Telitacicept Prompts Positive Responses in Lupus Treatment

Phase 2b study data also showed a dose reduction in glucocorticoids among those who received the investigational drug compared with patients who received placebo.

Union medical college hospitalPeking union medical college hospitalSystemic lupus erythematosus sle erythaematosusBiologic therapyGlucocorticoid therapyClinical researchClinical trialsLinical studiesPre clinical trialDouble blind studyDouble blind studiesIngle blind studyIngle blind studiesHealthcare and medical technology

COPD Exacerbations: BET With Prednisolone Noninferior to ST

Results of a randomized trial suggest that blood eosinophil-directed prednisolone can be an option to reduce glucocorticoid use in COPD patients.

United kingdomSanjay ramakrishnanUniversity of oxfordLancet respiratory medicineChronic obstructive pulmonary diseaseOpd chronic obstructive pulmonary diseaseChronic obstructive lung diseaseOad chronic obstructive airway disease coadOsinophil granulocytesQuality of lifeEalth related quality of lifeGlucocorticoid therapyPractice management

Efficacy and Safety of Tofacitinib in Patients with Polymyalgia Rheumatica (EAST PMR): An open-label randomized controlled trial

Xinlei Ma and co-workers investigate tofacitinib as a possible treatment for patients with polymyalgia rheumatica.

Eteläuomen läiChina national centerNational key researchZhejiang university school of medicineNational genomics data center nucleic acids resChinese academy of sciencesBioinformation beijing institute of genomicsDevelopment program of chinaLibrary prep kit for illuminaEthical committee of the first affiliated hospitalNatural science foundation of chinaFirst affiliated hospitalZhejiang university schoolPolymyalgia rheumaticaCreative commons attribution licenseGenome sequence archive

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