The selected projects will receive a total of €95m over the next three years.
These include technologies that aim to improve outcomes for cancer patients, projects that use drones to detect drug smuggling and projects that use artificial intelligence to make factories safer.
So far, €235m has been allocated out of the total fund of €500m.
Tánaiste and Minister for Enterprise, Trade and Employment Leo Varadkar said his department is funding projects which will have wide-ranging benefits across many areas of society. There are many successful projects in the health sector, which we hope will result in better patient outcomes for thousands suffering from cancer, heart disease and fractured bones among other conditions.