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Sensitive and specific serological ELISA for the detection of SARS-CoV-2 infections | Virology Journal

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered the worldwide coronavirus disease 2019 (COVID-19) pandemic. Serological assays for the detection of SARS-CoV-2 infections are important to understand the immune response in patients and to obtain epidemiological data about the number of infected people, especially to identify asymptomatic persons not aware of a past infection. We recombinantly produced SARS-CoV-2 nucleocapsid (N)-protein in Escherichia coli. We used t...
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