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Novel Therapeutic Approach against Cancer Revealed

Researchers at the University of North Carolina (UNC) at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development. They then developed a new therapeutic approach with a potent small-molecule inhibitor of this enzyme.
Lineberger Greg Wang Lineberger Comprehensive Cancer Center School Of Medicine Icahn School Of Medicine At Mount Sinai University Of North Carolina North Carolina

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Novel small-molecule therapy shows promise against deadly pediatric leukemia

Mount Sinai researchers have developed a therapy that shows promise against a deadly pediatric leukemia. The small-molecule therapy was highly effective in fighting a type of acute myeloid leukemia in both in vitro and in vivo experiments, according to research published in Science Translational Medicine in September.
Jian Jin Aneel Aggarwal Greg Wang Emily Henderson University Of North Carolina At Chapel Hill Icahn School Of Medicine At Mount Sinai

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