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Guselkumab Benefits Ulcerative Colitis Regardless of Patient Treatment History

New QUASAR analysis shows patients with intolerance or failed response to advanced therapies nonetheless achieved benefit with guselkumab.

British columbiaLinkedin brian bresslerBrian bresslerAmerican college of gastroenterologyAmerican collegeScientific meetingAcg 2023Ulcerative colitisPhase 3

Guselkumab Leads to Rapid Ulcerative Colitis Symptom Improvement

Induction treatment with guselkumab resulted in a rapid onset of efficacy, beginning at week 1 and increasing over time to week 12, for patients with refractory moderately to severely active ulcerative colitis.

British columbiaAmerican college of gastroenterologyUniversity of pennsylvania gary lichtensteinGary lichtensteinAmerican collegeScientific meetingSeverely active ulcerative colitisUlcerative colitis

Guselkumab Demonstrates Long-Term Benefit for Crohn Disease

During the long-term extension of the GALAXI trial, 54.1% of participants treated with guselkumab achieved clinical remission and 34.7% achieved endoscopic response.

Jan wehkampAnita afzaliUc health anita afzaliUniversity of cincinnati college medicineJohnson innovative medicinesUnited european gastroenterology weekCincinnati collegeJohnson innovativeSeverely active crohnParticipants with moderatelyAchieved clinical remissionCorticosteroid free remission throughInflammatory bowel diseaseCrohn diseaseCrohn x27s disease

TREMFYA® (guselkumab) Provides Sustained Improvements Across All Minimal Disease Activity Domains for Adults Living with Active Psoriatic Arthritis in Phase 3b Trial

TREMFYA® (guselkumab) Provides Sustained Improvements Across All Minimal Disease Activity Domains for Adults Living with Active Psoriatic Arthritis in Phase 3b Trial
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Spring houseUnited statesScandj rheumatolLaura coatesTerence rooneyZismand comorbiditiesJanssen pharmaceutical companies of johnsonJanssen pharmaceutical companiesDevices agencyUniversity of oxfordStanford health assessment questionnaireArthritis foundationJanssen scientific affairsEuropean congressNone of the janssen pharmaceutical companiesJanssen research development

Johnson & Johnson : Results of Novel Clinical Study of Guselkumab and Golimumab Combination Therapy Show Adults with Moderately to Severely Active Ulcerative Colitis Maintained Higher Rates of Clinical, Histologic, and Endoscopic Remission at Week 38

The rate of clinical remission was 47.9 percent in patients who received combination induction therapy with guselkumab and golimumab compared with either treatment alone at 38 weeks1 . | October 10, 2022

United statesSpring houseCraig stoltzBrucee sandsNone of the janssen pharmaceutical companiesCrohn colitis foundationSteering committeeJanssen research developmentJanssen pharmaceutical companiesJanssen pharmaceutical companies of johnsonExchange commissionIcahn school of medicine at mount sinaiCompanies of johnsonColitis organisationCrohn colitis foundation of americaUnited european gastroenterology