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<p><strong>The emergence of the SARS-CoV-2 variant JN.1 has sparked global concern due to its distinct genetic features and heightened infectivity. Carrying over 30 spike protein mutations, including the hallmark Leu455Ser, JN.1 exhibits substantial potential for immune evasion. Researchers from Japan have revealed JN.1&#39;s worldwide dominance, as it surpasses other variants in reproductive numbers. Novel findings indicate JN.1&#39;s robust resistance to immunity, emphasizing the urgent need for research strategies to address its threat to public health.</strong></p>

United kingdomKei satoKaho okumuraGyu kakuJumpei itoInstitute of medical scienceUniversity of tokyoMethod of researchMedical scienceLancet infectious diseasesProf kei