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Brazil reported a third case of the Omicron coronavirus variant on Wednesday, casting doubt on plans to loosen containment curbs ahead of year-end holidays in response to a fall in infection numbers.

Massachusetts Governor Charlie Baker, a popular Republican leader in a Democratic stronghold, said on Wednesday he will not seek a third term in 2022.

U.S. lawmakers' efforts to keep the U.S. government operating hit a stumbling block on Wednesday as a group of hard-line Republicans threatened to try to block any plan that allowed COVID-19 vaccine mandates to proceed.

The Omicron variant has been detected in five out of nine South African provinces and accounted for 74% of the virus genomes sequenced in November, data from the country's National Institute for Communicable Diseases (NICD) showed on Wednesday.

Conservative U.S. Supreme Court justices on Wednesday indicated support for upholding a restrictive Mississippi abortion law in a ruling that would undermine or outright overturn the landmark 1973 Roe v. Wade ruling legalizing the procedure nationwide.

The World Health Organization expects to have more information on the transmissibility of the new Omicron variant of the coronavirus within days, its technical lead on COVID-19, Maria van Kerkhove, said in a briefing on Wednesday.

Italy's medicines agency AIFA on Wednesday gave the go-ahead for the use of Pfizer-BioNTech's COVID-19 vaccine for children between the ages of five and 11.

Cuban health authorities said that researchers in the communist-run country are upgrading its homegrown COVID vaccines to ensure protection against the new Omicron variant.

New infections and deaths from HIV/AIDS may increase as the COVID-19 pandemic has disrupted prevention measures, said UNAIDS Executive Director Winnie Byanyima in an interview airing on Wednesday at the Reuters Next conference.

The U.S. Supreme Court on Wednesday heard arguments in Washington centered on a Mississippi law banning abortion after 15 weeks of pregnancy in a case that could lead to a dramatic rollback of abortion rights in America. Here are some key quotes from the oral argument.