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Opinion: The pandemic forced my wife to fight our insurer over hormones

GUNNISON- For the past eight years, my wife, Ky Hamilton, has undergone gender-affirming hormone therapy. That was until she lost her job in April 2020 and we switched to a subsidized private health insurance plan in Colorado's Affordable Care Act marketplace. We discovered that our new insurance from Anthem doesn't cover Depo-Estradiol and it would cost $125.

ما هي مخاطر الجمع بين أكثر من دواء في وقت واحد؟

ما هي مخاطر الجمع بين أكثر من دواء في وقت واحد؟
bbc.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from bbc.com Daily Mail and Mail on Sunday newspapers.

Droplets of Unsaturated Fats Burden Human ApoE4 Astrocytes

12 Mar 2021 The E4 allele of the apolipoprotein E, a strong risk factor for many neurodegenerative diseases, most prominently late-onset Alzheimer’s disease, upsets the balance of lipids within cells. Exactly how ApoE4 does this remains unclear. In the March 3 Science Translational Medicine, researchers led by Li-Huei Tsai at MIT found that in human astrocytes and microglia, ApoE4 increased the amount of unsaturated lipids, which then accumulated in lipid droplets. Adding the phospholipid precursor choline to the cells restored their normal lipid metabolism, hinting at potential therapeutic approaches for ApoE4 carriers. How exactly does ApoE4 lead to lipid imbalance in astrocytes?

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