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Podcast: A year later, scientists recall efforts to jump-start research into mysterious new coronavirus – Washington University School of Medicine in St Louis

Matt Miller Michael S. Diamond, MD, PhD, (left) and Sean Whelan, PhD, collaborate on research into the virus that causes COVID-19. Early in the pandemic, they cooperated to build a laboratory where the novel coronavirus could be studied. A new episode of our podcast, “Show Me the Science,” has been posted. At present, these podcast episodes are highlighting research and patient care on the Washington University Medical Campus as our scientists and clinicians confront the COVID-19 pandemic. Even before the first case of COVID-19 was reported in the United States, Michael S. Diamond, MD, PhD, the Herbert S. Gasser Professor of Medicine, started setting the stage with Sean Whelan, PhD, the Marvin A. Brennecke Distinguished Professor of Molecular Microbiology, for scientists at the university to study the virus. Whelan had just arrived in St. Louis to begin his new role as head of the Department of Molecular Microbiology and didn’t even have an operational laboratory when the tw

COVID-19 Can Kill Heart Cells and Interfere With Contraction

COVID-19 Can Kill Heart Cells and Interfere With Contraction Study reveals details of how coronavirus infects the heart and heart damages cardio myocytes A study from Washington University School of Medicine in St. Louis provides evidence that the coronavirus can invade and replicate inside heart muscle cells, causing cell death and interfering with heart muscle contraction. The image of engineered heart tissue shows human heart muscle cells (red) infected with COVID-19 (SARS-CoV-2) (green). Image by Lina Greenberg. March 12, 2021 Since early in the pandemic, COVID-19 has been associated with heart problems, including reduced ability to pump blood and abnormal heart rhythms. But it has been an open question whether these problems are caused by the virus infecting the heart, or an inflammatory response to viral infection elsewhere in the body. Such details have implications for understanding how best to treat coronavirus infections that affect the heart. A new study from Washing

SARS-CoV-2 Variants Can Evade Antibodies That Neutralize Original Virus

COVID-19 Antibodies, Vaccines Less Effective against Variants

Worrisome new coronavirus variants can evade antibodies that neutralize original virus, recent lab research shows March 8, 2021 Physician assistant Philana Liang prepares a vial of COVID-19 vaccine on the Washington University Medical Campus. New research from Washington University School of Medicine in St. Louis has found that new variants of the virus that causes COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic, potentially undermining the effectiveness of vaccines and antibody-based drugs now being used to prevent or treat COVID-19. Matt Miller/Washington University New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic. With few exceptions, whether such antibodies were produced in response to vaccination or natural infection, or w

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