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Doctors are heralding an extraordinary transformation, in the treatment of a deadly form of skin cancer. Ten years ago advanced melanoma was seen as untreatable, but a Clinical Trial shows half of patients are now surviving for at least five years. The drugs involved target the immune system, and are already available on the nhs. Our health and science correspondent James Gallagher reports. Pam smith is alive and well, but its been more than five years since she had the devastating news that her...

And crunch time for wales, as they take australia at the rugby world cup. Hello, good morning. Nota particularly cheery picture behind me, and that is the way of it across england and wales this morning. It is pretty wet and windy fair for many. Something a little bit better for scotland and Northern Ireland. I will have all the details for you in just a few minutes. It is sunday 29 september. Our top story the conservative Party Conference opens later with a promise to get brexit done. There is...

All made out of plastic. Seems appropriate. For some people, this toy is a bit like a religion. Lets see what the weather is doing for us. We heard about the flood warnings in what could be to come lets get a full forecast. Hello, after a wet and windy night we are not quite done yet with this combination of weather. Thanks to that area of low pressure, not such an issue across scotla nd pressure, not such an issue across scotland and Northern Ireland although it was wet in Northern Ireland, thi...

Flown back to the uk. Judith moritz reports. They flew all over the globe for thomas cook, now their world has come crashing down. Jobs gone, livelihoods destroyed. When the airline folded, jo was one of the cabin crew left stranded abroad. When she got home, things went from bad to worse. Im now homeless, my landlord is now demanding i leave the property, so i am having to wait for the local council to see if they can put me in sheltered accommodation. So you cant pay the rent, the landlord has...

Ahead and while there is some sunshine the forecast there is also heavy rain and strong winds. All of the details in the next half an hour. Its saturday the 28th of september. Our top story downing street has reacted angrily after Boris Johnson was referred to the Police Watchdog over his friendship with an american businesswoman. The independent office for Police Conduct will look at whether a criminal investigation should be launched into allegations thatjennifer arcuri was given favourable tr...

Proposed new laws on Domestic Abuse are a once in a Generation Opportunity to help victims. That was theresa mays message in her first speech in the commons, since resigning as prime minister. Mrs mays government introduced the Domestic Abuse bill injuly, but its progress was delayed when borisjohnson suspended parliament. During the debate the labour mp Rosie Duffield shared her own experience of Domestic Abuse, as our Political Correspondent Jessica Parker reports. A loving partner shouldnt ta...

Midlands, into lincolnshire, could bea midlands, into lincolnshire, could be a miserable day for someone sunday. As that area of low pressure begins to pull away later on sunday, we will get another swathe of strong wind, gusts reaching 45 50 miles per across parts of eastern england. We say goodbye to that area of low pressure and into the new working week, we have another one with a repeat performance. We could see another 70 millimetres of rain over the hills of wales. It has been a wet spell...