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Paolo Macchiarini misled the world over his breakthroughs in regenerative medicine, but why did most of the institutions that supported him bear no responsibility for hosting a rogue stem cell surgeon? It’s time for them to launch full and independent investigations, argue John Rasko and Carl Power
By 2008 it looked like a medical revolution was under way. Before us lay a new world, where any injured organ could be replaced with one custom-made in the laboratory. Leading us there was the charismatic Italian surgeon Paolo Macchiarini, who’d begun replacing damaged windpipes with tissue engineered ones. Each was made of a scaffold and seeded with the patients’ own stem cells, which were meant to turn it into a living, functioning organ. The era of “regenerative medicine” was upon us.
But early 2016 woke us from this dream. Swedish television broadcast Experimenten , a blistering three part investigation into Macchiarini,1 exposing him as a charlatan whose engineered windpipes did more harm than good, something he’d lied about for years. The scandal ruined his career and shook his Swedish employer, the Karolinska Institute, to its very foundations.2 Home to the Nobel Prize in medicine, this illustrious university was dubbed by some as the “Chernobyl of ethics.”
The Karolinska later found Macchiarini guilty of scientific misconduct and called for several of his articles to be retracted.3 Many commentators expected that he would finish his career behind bars for the deaths of his three Karolinska patients, but that hasn’t happened. After years of delay a Swedish court acquitted Macchiarini of five of the six charges against him, convicting him of harming just one person through negligence. The punishment? A suspended sentence of two years’ probation. Macchiarini’s lawyer was so pleased he dubbed it a “five-sixths victory.” Not that the case is …
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