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What happens when a $3m gene therapy is not enough

LOS ANGELES - Baby Ben Kutschke was diagnosed at three months with spinal muscular atrophy, a rare inherited disorder which is the leading genetic cause of death in infancy globally. It leaves children too weak to walk, talk, swallow or even breathe. So when in 2021 his parents heard about Zolgensma โ€“ a one-time therapy costing millions of dollars that...
United States Russell Butterfield Ben Kutschke Stacie Dusetzina Sitra Tauscher Wisniewski Jerry Mendell

Breakthrough in solid-state storage innovates

Scientists have developed a novel method for storing biological materials in the form of a pill or a tablet, which dissolves in water for on-demand use. The innovation could overcome current limitations involving in the storage and handling of products derived from living cells used for a variety of health care and scientific research purposes, including pharmaceuticals and diagnostic testing tools.
United States Luis Obispo Development Of Solid California Polytechnic State University Cal Method Of Research Institute For Human Data Science

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Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation

As antibiotic resistance increases globally, antibiotic innovation is struggling. WHO states that the antibiotic clinical pipeline is โ€œinsufficient to tackle the challenge of increasing emergence and spread of antimicrobial resistanceโ€.1 To prevent the development of resistance, new antibiotics are used as last resort treatments and, if properly used, have small patient populations, resulting in fairly low sales revenues for industry.
France General United Kingdom Bruxelles Capitale City Of The Netherlands Regional Office For Europe

CNN CNN Newsroom Live June 4, 2024 09:44:00

>> we think that using what weve done before we should be able to appropriately respond to this current outbreak. >> reporter: and while the variant responsible for this particular outbreak the sudan virus does not currently have a vaccine, trials could start in four to six weeks. >> there are about six candidates, vaccine candidates, available for the sudan ebola virus which are mostly in very early stages of development, but three of them have some human data, some immunogenicity and safety da...
Vaccine Candidates Sudan Ebola Virus Train Vaccination Health Workers Human Data Oxford University

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