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Research finds link between drug resistance of leukaemia cells and mitochondria

Leukemic cells often adopt features that let them evade the drugs effects within a year.

United statesXufeng chenHermannm biggsChristina glytsouIannis aifantisLangone healthRutgers universityPerlmutter cancer centerGrossman school of medicineDepartment of pathologyCancer discoveryEws india

Drug Combination Restores Ability of Leading Treatment to Signal for Death of Blood Cancer Cells

/PRNewswire/ Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt.

United statesUnited kingdomNew yorkMichael cammerChristina glytsouTomasz zalMalgorzata anna zalBettina nadorpWafa al santliAristotelis tsirigosAudrey lasryBing carterKun wangHua zhouXufeng chenEvripidis gavathiotis

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.

United statesUnited kingdomNew yorkEmily hendersonIannis aifantisBing carterHermannm biggsMichael andreeffJo ishizawaKun wangDimitrios papaioannouSoobeom leeMichael cammerMalgorzata anna zalEvripidis gavathiotisXufeng chen

Drug combination restores ability of leading

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs’ effects within a year.

United statesNew yorkUnited kingdomAudrey lasryRaoul tibesEvripidis gavathiotisMichael cammerMichael andreeffZhengxi sunIannis aifantisDimitrios papaioannouSoobeom leeHua zhouChristina glytsouWafa al santliBettina nadorp

Drug combination restores ability of leading treatment to signal for death of blood cancer cells: Future clinical trials to determine if combination chloroquine and venetoclax addresses disease comeback

Drug combination restores ability of leading treatment to signal for death of blood cancer cells: Future clinical trials to determine if combination chloroquine and venetoclax addresses disease comeback
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United statesUnited kingdomNew yorkBing carterZhengxi sunAudrey lasryEvripidis gavathiotisHermannm biggsTomasz zalEmmanouil zacharioudakisRaoul tibesJo ishizawaBettina nadorpMalgorzata anna zalHua zhouWafa al santli