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High-fat diet accelerates aging-related memory loss in rats

Study found that a high-fat diet exacerbates age-related cognitive decline in rats, even when microglia cells are removed from the equation, suggesting other pathways may play a role.

Aging
Iet
Icroglia
Nxiety
Lood
Lood-pressure
Ody-mass-index
Rain
Ancer
Ardiovascular-disease
Epression

Unlocking glioblastoma's immune suppression mechanism

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

Filippo-veglia
Wistar-institute
Assistant-professor
Brain
Rain-cancer
Ancer
Ioinformatics
Ene
Ene-expression
Lioblastoma
Lucose
Glucose-metabolism

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

San-diego
California
United-states
University-of-california-san-diego
Xu-chen
Lingyan-shi
Yajuan-li
Alois-alzheimer
Shu-chien
Jacobs-school
Uc-san-diego-jacobs-school-of-engineering
University-of-california

Mapping the brain: How cell types and location influence Parkinson's disease

A single-cell spatial transcriptome analysis on murine brain expression in age and disease using a Parkinson's disease.

Cell-reports
Uniform-manifold-approximation
Brain
Ell
Ging
Alcium
Dopaminergic
Ish
Ene
Ene-expression
Enes

COVID-19's neurological effects linked to immune response, not direct viral attack

Study identifies neurocognitive symptoms in COVID-19 patients as a reaction to systemic infection rather than direct brain infection, highlighting changes in the brain's immune response and synaptic organization.

Rattiya-thongdumhyu
Nature-neuroscience
Brain
Oronavirus-disease-covid-19
Lood
Rain-fog
Ell
Entral-nervous-system
Oronavirus
Atigue
Enes

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) – the biggest genetic risk factor for late-onset Alzheimer's disease.

Sarah-cohen
Ian-windham
Rockefeller-university
School-of-medicine
University-of-north-carolina-health-care
North-carolina-health
Alois-alzheimer
Protein
Lzheimer-39s-disease
Apolipoprotein
Astrocyte

Enzyme released by immune cells may play role in depression

Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors.

Leon-levy
Flurin-cathomas
Scott-russo
Mount-sinai-health-system
Body-research-center
Body-research-center-at-mount-sinai
Sinai-health
Brain-body-research-center
Mount-sinai-professor
Affective-neuroscience
Leon-levy-director
Mount-sinai

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