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Dosage regimen enable BF211 to like a drug, providing a promising nano platform to deliver the cardiac glycosides and alleviate side effects

The mechanism by which the LNC00115/miR-7/ERK axis promotes cisplatin resistance provides a new strategy for combating cisplatin resistance in ovarian cancer

Microvessel Density is Increased in Human GC Tissues To confirm the association between Nrf2/HO-1 and angiogenesis in GC, we also determined the microvessel density of these human GC samples. Consistently, the microvessel density was low in paracancerous tissues, but high in GC. Moreover, the microvessel density was low, moderate, and high in well-, moderately-, and poorly differentiated GC, respectively (Figure 8). Collectively, the Nrf2/HO-1 axis is likely to participate in the malignant proc...

D) Immunohistochemical staining of COX-2 and iNOS inflammatory factors in liver tissue. ( E and F) Inflammatory cell expression area %Data are presented as the mean±SD (n=10). As compared with the normal group, # ## P

1 2Medical Records Management Division, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China; 3Intensive Care Unit, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China; 4Pharmacy Services, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China *These authors contributed equally to this work Correspondence: Dehong Huang Department of Hematology and Oncology, Chongqing University Cancer Hospital, No. 181 Hanyu Road, Chong...

1Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China 2Luzhou Key Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, China 3Academician (Expert) Workstation of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China 4Sichuan Clinical Research Center for Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou, China Subarachnoi...

G), invasion rate ( H, I) in vitro model of LNCap cell. *p 0.01 compared with negative group, #p 0.01 compared with down-regulation of RAMS11 group. Abbreviations: Negative, negative mimics group; SiRAMS11, down-regulation of RAMS11 group; Top2α, over-expression of Top2α group. Discussion The treatment of prostate cancer is mainly determined by objective factors, including patient age, physical condition, clinical stage, Gleason score, presence or absence of pelvic lymph nodes, distant metas...