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Study investigates long-term sequelae of COVID-19 in hospitalized children

Study investigates long-term sequelae of COVID-19 in hospitalized children Researchers from ISARIC (International Severe Acute Respiratory and emerging Infection Consortium) pediatric Long Covid working group in the UK, Sechenov University and Z.A. Bashlyaeva Children s Municipal Clinical Hospital in Russia ran the largest study to date on children hospitalized with COVID-19. The study aimed to discover what the long-term effects are on children and adolescents who have been hospitalized with confirmed COVID-19. They also aimed to discover the risks of children developing long term symptoms after being diagnosed with COVID-19. According to the study, older children are at greater risk of developing Long COVID as well as children with allergic diseases reported by their parents. In the telephone interviews, parents reported mainly fatigue, changes in their taste or smell and sleeping problems, most commonly insomnia.

University of Oxford to launch Pandemic Sciences Centre

Key lesson from the coronavirus pandemic is the need for partnership between academic excellence, industry and public health organisations. Centre will unite disciplines, and sectors, to build agile, equitable partnerships that can tackle complex problems and respond to pandemic threats at any time. Centre will build on the UK and international reach of Oxford s research collaborations.

Precision Medicine for COVID-19: Phenotype Anarchy or Promise Realized? | Coronavirus (COVID-19) | JAMA

Hala T. Borno, MD; Jennifer R. Rider, ScD, MPH; Christine M. Gunn, PhD A taxonomic revolution is occurring in medicine. Spurred by the halcyon vision of targeted “precision” therapy and enabled by access to massive electronic health data sets, high-throughput multichannel, molecular diagnostic assays, and advances in the understanding of disease biology, researchers have generated a plethora of new disease subclassifications (eTable and eFigure in the Supplement). Variably termed “phenotypes,” “endotypes,” or “subtypes,” these patient groups can share symptoms, biology, or prognosis and are proposed as the basis for precision care. The fast-paced research of SARS-CoV-2 has followed suit, with more than 60 subtypes proposed in the last year (eTable and eFigure in the Supplement). These subtypes range from simple classifications such as the

Covid vaccine: One in 14 hospital patients with disease had had first dose

PREMIUM The study is tracking cases of hospital admission for Covid among patients who have been vaccinated, versus those unvaccinated. At this stage the data covers first doses rather than second. ONE in 14 patients admitted to hospital since Britain s vaccine rollout began had had at least their first inoculation, with over 100 mostly frail elderly patients dying with Covid more than three weeks after receiving the jag. Scientists stressed that the findings were to be expected and that a steep decline in admissions among immunised individuals was clear evidence that the vaccines are working. The data emerged in the latest publication from the Isaric (International Severe Acute Respiratory and Emerging Infection Consortium) study, which is tracking Covid hospitalisations among vaccinated and unvaccinated patients in Scotland, England, and Wales.

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