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Mutant UK Covid-19 Strain May Force Serum Institute to Tweak Vaccine Composition
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Serum Institute of India may have to make adjustments in the composition of the vaccine developed by the University of Oxford and British pharma major AstraZeneca after the World Health Organization’s (WHO) Strategic Advisory Group of Experts on Immunization (SAGE) expressed concerns over the effectiveness of the vaccine against the South African mutant coronavirus strain.
According to a report by Mint, on Monday and Tuesday, SAGE reviewed the evidence on the vaccine’s effectiveness on new SARS CoV-2 variants, before making significant recommendations.
Earlier, South Africa decided to stop the rollout of the Oxford-AstraZeneca vaccine after preliminary clinical trial findings published by the Wits Vaccines and Infectious Diseases Analytics Research Unit indicated that it offered minimal protection against the mild-moderate Covid-19 infection from the B.1.351 variant of the coronav
Serum Institute may alter covid shot to tackle mutant strain
Named as covishield in India, the Oxford-AstraZeneca vaccine has been rolled out in the country but is yet to receive a green signal for global use through COVAX
(REUTERS)
on Monday and Tuesday, SAGE reviewed the evidence on jab’s effectiveness on new SARS CoV-2 variants
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The composition of the vaccine developed by the University of Oxford and British pharma major AstraZeneca may have to be adjusted by vaccine manufacturer Serum Institute of India, after the World Health Organization’s (WHO) Strategic Advisory Group of Experts on Immunization (SAGE) expressed concerns over the effectiveness of the vaccine against the South African mutant coronavirus strain.
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The number of known coronavirus variant cases in the U.S. has surged 73% in the last week alone, according to figures from the Centers for Disease Control and Prevention released late Tuesday.
The country now reports 944 cases of variants that spread more easily, bypass treatments and immunities, or both.
2 February 2021 - Wits University
Researchers at the University of Oxford have today published in Preprints with The Lancet an analysis of further data from the ongoing trials of the vaccine.
The Vaccines and Infectious Diseases Analytics Research Unit (VIDA) at Wits University runs the South African Oxford Covid-19 vaccine trial. Professor Shabir Madhi, Executive Director of Wits VIDA and Dean of the Faculty of Health Sciences at the University, leads these trials and he is a co-author in the Preprints.
In releasing the data regarding sustained protection of 76% during the 3-month interval until the second dose, scientists at Oxford reveal that the vaccine efficacy is higher at longer prime-boost intervals, and that a single dose of the vaccine is 76% effective from 22- to up to 90-days post vaccination. The analyses reveal: