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Frontiers | Emergence of Dengue 4 as Dominant Serotype During 2017 Outbreak in South India and Associated Cytokine Expression Profile

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for...
United States United Kingdom New Delhi Tamil Nadu Sri Lanka Republic Of

Confirmado: la COVID-19 ataca al cerebro. Pero aún no saben cómo

Profesor e Investigador Científico en Neurociencias, Universidad Complutense de Madrid Madrid, 28 de junio (The Conversation).- A finales de 2019 se confirmaron los primeros casos de infección por SARS-CoV-2. Tal y como su nombre indica (SARS viene del inglés Severe Acute Respiratory Syndrome), se trata de un virus que afecta al tracto respiratorio produciendo síntomas característicos como congestión nasal, dificultad para respirar. A medida que la pandemia avanzaba, aumentó el núm...
United States United Kingdom Saarland Stanford Research Scientist University Complutense Madrid Moral Professor

iTeos Therapeutics Announces New Preliminary Data Indicating Clinical Activity with its ...

Press release content from Globe Newswire. The AP news staff was not involved in its creation. iTeos Therapeutics Announces New Preliminary Data Indicating Clinical Activity with its ... iTeos Therapeutics Inc.April 10, 2021 GMT Initial data from the Phase 1 dose escalation part of the Phase 1/2a trial in adult patients with advanced solid tumors indicated EOS-448 was generally well tolerated with no dose-limiting toxicities observed EOS-448 showed preliminary signs of clinical activity as a mo...
United Kingdom United States Waals Gewest Mario Sznol Joanne Jenkins Lager Bryan Baker
Source: apnews.com

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iTeos Therapeutics Announces New Preliminary Data Indicating Clinical Activity with its Anti-TIGIT Antibody, EOS-448, at the AACR Annual Meeting 2021

Share: Initial data from the Phase 1 dose escalation part of the Phase 1/2a trial in adult patients with advanced solid tumors indicated EOS-448 was generally well tolerated with no dose-limiting toxicities observed EOS-448 showed preliminary signs of clinical activity as a monotherapy, including a partial response in one pembrolizumab-resistant melanoma patient, and stable disease in multiple patients EOS-448 reduced TIGIT + suppressive T regulatory cells and CD8 T cells considered to be ex...
United Kingdom United States Waals Gewest Mario Sznol Joanne Jenkins Lager Bryan Baker

iTeos Therapeutics Inc.: iTeos Therapeutics Announces New Preliminary Data Indicating Clinical Activity with its Anti-TIGIT Antibody, EOS-448, at the AACR Annual Meeting 2021

(0) Initial data from the Phase 1 dose escalation part of the Phase 1/2a trial in adult patients with advanced solid tumors indicated EOS-448 was generally well tolerated with no dose-limiting toxicities observed EOS-448 showed preliminary signs of clinical activity as a monotherapy, including a partial response in one pembrolizumab-resistant melanoma patient, and stable disease in multiple patients EOS-448 reduced TIGIT + suppressive T regulatory cells and CD8 T cells considered to be exhau...
United Kingdom United States Waals Gewest Mario Sznol Joanne Jenkins Lager Bryan Baker

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