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A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

The ability to extract multigenerational family relationships from large-scale population cohorts provides a powerful means to understand the heritability of a wide range of diseases and their genetic relationships to each other. By showing how the heritability of broad diagnostic categories changes over time and how said categories are related on the genetic level, our analysis of the Danish genealogy and linked national patient registers illustrates the vast potential of this resource in curre...
Danish Data Protection Agency Danish Psychiatric Central Research Register European Union Horizon Innovation Programme National Health Registers Danish National Research Foundation
Source: pnas.org

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Cervical samples could reveal risk of breast and ovarian cancer

An international team of scientists, including from Karolinska Institutet, has discovered a means of identifying the risk of breast and ovarian cancer by analysing cell samples from the cervix. By measuring epigenetic changes in cervical samples from over a thousand women, the researchers have found two unique signatures for breast and ovarian cancer. The results are presented in two papers in the journal Nature Communications.
United Kingdom Karolinska Institutet Kristina Gemzell Danielsson Jamese Barrett Martin Widschwendter Innovation Programme
Source: news.ki.se

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